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PDCD4 controls the G1/S-phase transition in a telomerase-immortalized epithelial cell line and affects the expression level and translation of multiple mRNAs

PDCD4, the protein encoded by the tumor suppressor gene PDCD4 (programmed cell death 4) has been implicated in the control of cellular transcription and translation by modulating the activity of specific transcription factors and suppressing the translation of mRNAs with structured 5′-UTRs. Most stu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Haas, Astrid, Nilges, Benedikt S., Leidel, Sebastian A., Klempnauer, Karl-Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026441/
https://ncbi.nlm.nih.gov/pubmed/32066800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59678-w
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