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c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells
RORγt(+) group 3 innate lymphoid cells (ILC3s) maintain intestinal homeostasis through secretion of type 3 cytokines such as interleukin (IL)−17 and IL-22. However, CCR6(-) ILC3s additionally co-express T-bet allowing for the acquisition of type 1 effector functions. While T-bet controls the type 1...
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| Veröffentlicht in: | eLife |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7025824/ https://ncbi.nlm.nih.gov/pubmed/32039762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52549 |
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