c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells

RORγt(+) group 3 innate lymphoid cells (ILC3s) maintain intestinal homeostasis through secretion of type 3 cytokines such as interleukin (IL)−17 and IL-22. However, CCR6(-) ILC3s additionally co-express T-bet allowing for the acquisition of type 1 effector functions. While T-bet controls the type 1...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Tizian, Caroline, Lahmann, Annette, Hölsken, Oliver, Cosovanu, Catalina, Kofoed-Branzk, Michael, Heinrich, Frederik, Mashreghi, Mir-Farzin, Kruglov, Andrey, Diefenbach, Andreas, Neumann, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Immunology and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025824/
https://ncbi.nlm.nih.gov/pubmed/32039762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52549
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