c-Maf regulates the plasticity of group 3 innate lymphoid cells by restraining the type 1 program

CCR6(−) group 3 innate lymphoid cells (ILC3s) are mediators of intestinal immunity and barrier function that possess the capacity to acquire type 1 effector features and fully convert into ILC1s. The molecular mechanisms governing such plasticity are undefined. Here, we identified c-Maf as an essent...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Med
Prif Awduron: Parker, Morgan E., Barrera, Alejandro, Wheaton, Joshua D., Zuberbuehler, Matthew K., Allan, David S.J., Carlyle, James R., Reddy, Timothy E., Ciofani, Maria
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2019
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037249/
https://ncbi.nlm.nih.gov/pubmed/31570496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191030
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