Ligand-Guided Selection with Artificially Expanded Genetic Information Systems against TCR-CD3ε

Here we are reporting, for the first time, a ligand-guided selection (LIGS) experiment using an artificially expanded genetic information system (AEGIS) to successfully identify an AEGIS–DNA aptamer against T cell receptor-CD3ε expressed on Jurkat.E6 cells. Thus, we have effectively combined the enh...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Zumrut, Hasan, Yang, Zunyi, Williams, Nicole, Arizala, Joekeem, Batool, Sana, Benner, Steven A., Mallikaratchy, Prabodhika
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025805/
https://ncbi.nlm.nih.gov/pubmed/31880917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00919
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