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Dimerization of an aptamer generated from Ligand-guided Selection (LIGS) yields a high affinity scaffold against B-cells
Nucleic Acid Aptamers (NAAs) are a class of synthetic DNA or RNA molecules that bind specifically to their target. We recently introduced an aptamer termed R1.2 against membrane Immunoglobulin M (mIgM) expressing B-cell neoplasms using Ligand Guided Selection (LIGS). While LIGS-generated aptamers ar...
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| Pubblicato in: | Biochim Biophys Acta Gen Subj |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6248343/ https://ncbi.nlm.nih.gov/pubmed/30342154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2018.10.006 |
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