Anemonin Attenuates RANKL-Induced Osteoclastogenesis and Ameliorates LPS-Induced Inflammatory Bone Loss in Mice via Modulation of NFATc1

Osteoporosis is a metabolic bone disease characterized by insufficient osteoblastic function and/or excessive osteoclastic activity. One promising strategy for treating osteoporosis is inhibiting excessive osteoclast resorbing activity. Previous studies have revealed that anemonin (ANE), isolated fr...

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Publicado en:Front Pharmacol
Autores principales: Hou, Huanhuan, Peng, Qisheng, Wang, Shaoming, Zhang, Yuxin, Cao, Jinjin, Deng, Yuming, Wang, Yingjian, Sun, Wan-chun, Wang, Hong-bing
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025528/
https://ncbi.nlm.nih.gov/pubmed/32116686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01696
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