Nardosinone Suppresses RANKL-Induced Osteoclastogenesis and Attenuates Lipopolysaccharide-Induced Alveolar Bone Resorption

Periodontitis is a chronic inflammatory disease that damages the integrity of the tooth-supporting tissues, known as the periodontium, and comprising the gingiva, periodontal ligament and alveolar bone. In this study, the effects of nardosinone (Nd) on bone were tested in a model of lipopolysacchari...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Niu, Chenguang, Xiao, Fei, Yuan, Keyong, Hu, XuChen, Lin, Wenzhen, Ma, Rui, Zhang, Xiaoling, Huang, Zhengwei
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601052/
https://ncbi.nlm.nih.gov/pubmed/28955231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00626
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