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Loureirin B suppresses RANKL-induced osteoclastogenesis and ovariectomized osteoporosis via attenuating NFATc1 and ROS activities

Rationale: Osteoporosis is a severe bone disorder that is a threat to our aging population. Excessive osteoclast formation and bone resorption lead to changes in trabecular bone volume and architecture, leaving the bones vulnerable to fracture. Therapeutic approaches of inhibiting osteoclastogenesis...

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Liu, Yuhao, Wang, Chao, Wang, Gang, Sun, Youqiang, Deng, Zhangrong, Chen, Leilei, Chen, Kai, Tickner, Jennifer, Kenny, Jacob, Song, Dezhi, Zhang, Qingwen, Wang, Haibin, Chen, Zhenqiu, Zhou, Chi, He, Wei, Xu, Jiake
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643439/
https://ncbi.nlm.nih.gov/pubmed/31367247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.35414
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