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Simple FRET Electrophoresis Method for Precise and Dynamic Evaluation of Serum siRNA Stability

[Image: see text] Small interfering RNAs (siRNAs) are potent therapeutic molecules, but despite recent progress, their administration in vivo remains challenging due to their low stability in the bloodstream. Thus, techniques for investigating the stability of siRNA are fundamental for the developme...

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Publié dans:ACS Med Chem Lett
Auteurs principaux: Tuttolomondo, Martina, Ditzel, Henrik J.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2020
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025386/
https://ncbi.nlm.nih.gov/pubmed/32071688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00472
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