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Systematic design of DMBT1-derived peptides correlating physicochemical properties and sequence motifs with siRNA delivery and efficacy in cancer therapyResearch in context

Summary: Background: Molecules driving the cancer process are frequently difficult to target with traditional small-molecule drugs. Small interfering RNAs (siRNAs) offer high specificity, but their clinical translation is hindered by inefficient delivery and rapid degradation. We previously identif...

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Hlavní autoři: Martina Tuttolomondo, Mikkel Green Terp, Nazmie Kalisi, Stefan Vogel, Henrik Jørn Ditzel
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2025-11-01
Edice:EBioMedicine
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S2352396425004219
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