Systematic design of DMBT1-derived peptides correlating physicochemical properties and sequence motifs with siRNA delivery and efficacy in cancer therapyResearch in context

Summary: Background: Molecules driving the cancer process are frequently difficult to target with traditional small-molecule drugs. Small interfering RNAs (siRNAs) offer high specificity, but their clinical translation is hindered by inefficient delivery and rapid degradation. We previously identif...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Martina Tuttolomondo, Mikkel Green Terp, Nazmie Kalisi, Stefan Vogel, Henrik Jørn Ditzel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-11-01
coleção:	EBioMedicine
Assuntos:	Cell-penetrating peptides siRNA RNA interference Cancer therapy DMBT1
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352396425004219
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!