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Optimization of a Benzothiazole Indolene Scaffold Targeting Bacterial Cell Wall Assembly

BACKGROUND: The bacterial cell envelope is comprised of the cell membrane and the cell wall. The bacterial cell wall provides rigidity to the cell and protects the organism from potential harmful substances also. Cell wall biosynthesis is an important physiological process for bacterial survival and...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Chauhan, Jay, Yu, Wenbo, Cardinale, Steven, Opperman, Timothy J, MacKerell, Alexander D, Fletcher, Steven, de Leeuw, Erik PH
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024799/
https://ncbi.nlm.nih.gov/pubmed/32103898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S226313
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