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Synthetic Approaches to Zetekitoxin AB, a Potent Voltage-Gated Sodium Channel Inhibitor
Voltage-gated sodium channels (Na(V)s) are membrane proteins that are involved in the generation and propagation of action potentials in neurons. Recently, the structure of a complex made of a tetrodotoxin-sensitive (TTX-s) Na(V) subtype with saxitoxin (STX), a shellfish toxin, was determined. STX p...
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| Publicado no: | Mar Drugs |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7024329/ https://ncbi.nlm.nih.gov/pubmed/31888062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md18010024 |
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