DNA methylation-driven EMT is a common mechanism of resistance to various therapeutic agents in cancer

BACKGROUND: Overcoming therapeutic resistance is one of the major hurdles in cancer care. One mechanism contributing to therapeutic resistance is a process in which epithelial cells switch to a mesenchymal state (epithelial-to-mesenchymal transition or EMT). The precise mechanisms driving EMT-mediat...

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Publicat a:Clin Epigenetics
Autors principals: Galle, Eva, Thienpont, Bernard, Cappuyns, Sarah, Venken, Tom, Busschaert, Pieter, Van Haele, Matthias, Van Cutsem, Eric, Roskams, Tania, van Pelt, Jos, Verslype, Chris, Dekervel, Jeroen, Lambrechts, Diether
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7023776/
https://ncbi.nlm.nih.gov/pubmed/32059745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-0821-z
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