A Mechanistic Physiologically-Based Biopharmaceutics Modeling (PBBM) Approach to Assess the In Vivo Performance of an Orally Administered Drug Product: From IVIVC to IVIVP

The application of in silico modeling to predict the in vivo outcome of an oral drug product is gaining a lot of interest. Fully relying on these models as a surrogate tool requires continuous optimization and validation. To do so, intraluminal and systemic data are desirable to judge the predicted...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutics
Hauptverfasser: Bermejo, Marival, Hens, Bart, Dickens, Joseph, Mudie, Deanna, Paixão, Paulo, Tsume, Yasuhiro, Shedden, Kerby, Amidon, Gordon L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7023481/
https://ncbi.nlm.nih.gov/pubmed/31963448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12010074
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge