The Ubiquitin-Specific Protease Usp7, a Novel Merkel Cell Polyomavirus Large T-Antigen Interaction Partner, Modulates Viral DNA Replication

Merkel cell polyomavirus (MCPyV) is the major cause for Merkel cell carcinoma (MCC), a rare but highly aggressive skin cancer predominantly found in elderly and immunosuppressed patients. The early viral gene products large T-antigen (LT) and small T-antigen (sT) are important for efficient viral DN...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Czech-Sioli, Manja, Siebels, Svenja, Radau, Sonja, Zahedi, René P., Schmidt, Claudia, Dobner, Thomas, Grundhoff, Adam, Fischer, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022344/
https://ncbi.nlm.nih.gov/pubmed/31801860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01638-19
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