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RNA sequence and length contribute to RNA-induced conformational change of TLS/FUS
Translocated in liposarcoma (TLS)/fused in sarcoma (FUS) is a multitasking DNA/RNA binding protein implicated in cancer and neurodegenerative diseases. Upon DNA damage, TLS is recruited to the upstream region of the cyclin D1 gene (CCND1) through binding to the promotor associated non-coding RNA (pn...
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| Foilsithe in: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group UK
2020
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7021683/ https://ncbi.nlm.nih.gov/pubmed/32060318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59496-0 |
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