RNA sequence and length contribute to RNA-induced conformational change of TLS/FUS

Translocated in liposarcoma (TLS)/fused in sarcoma (FUS) is a multitasking DNA/RNA binding protein implicated in cancer and neurodegenerative diseases. Upon DNA damage, TLS is recruited to the upstream region of the cyclin D1 gene (CCND1) through binding to the promotor associated non-coding RNA (pn...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Hamad, Nesreen, Mashima, Tsukasa, Yamaoki, Yudai, Kondo, Keiko, Yoneda, Ryoma, Oyoshi, Takanori, Kurokawa, Riki, Nagata, Takashi, Katahira, Masato
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7021683/
https://ncbi.nlm.nih.gov/pubmed/32060318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59496-0
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