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Plastic roles of phenylalanine and tyrosine residues of TLS/FUS in complex formation with the G-quadruplexes of telomeric DNA and TERRA

The length of a telomere is regulated via elongation and shortening processes. Telomeric DNA and telomeric repeat-containing RNA (TERRA), which both contain G-rich repeated sequences, form G-quadruplex structures. Previously, translocated in liposarcoma (TLS) protein, also known as fused in sarcoma...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kondo, Keiko, Mashima, Tsukasa, Oyoshi, Takanori, Yagi, Ryota, Kurokawa, Riki, Kobayashi, Naohiro, Nagata, Takashi, Katahira, Masato
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809584/
https://ncbi.nlm.nih.gov/pubmed/29434328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21142-1
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