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Arginine methylation of translocated in liposarcoma (TLS) inhibits its binding to long noncoding RNA, abrogating TLS-mediated repression of CBP/p300 activity

Translocated in liposarcoma (TLS) is an RNA-binding protein and a transcription-regulatory sensor of DNA damage. TLS binds promoter-associated noncoding RNA (pncRNA) and inhibits histone acetyltransferase (HAT) activity of CREB-binding protein (CBP)/E1A-binding protein P300 (p300) on the cyclin D1 (...

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書目詳細資料
發表在:J Biol Chem
Main Authors: Cui, Wei, Yoneda, Ryoma, Ueda, Naomi, Kurokawa, Riki
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052218/
https://ncbi.nlm.nih.gov/pubmed/29784880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000598
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