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Human Cord Blood Serum-Derived APP α-Secretase Cleavage Activity is Mediated by C1 Complement
Alzheimer’s Disease (AD) is the leading cause of dementia in the elderly. In healthy individuals, amyloid precursor protein (APP) is cleaved by α-secretase, generating soluble α-amyloid precursor protein (sAPPα), which contributes neuroprotective functions in the neuronal environment. In contrast, i...
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| Publicado en: | Cell Transplant |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
SAGE Publications
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7020233/ https://ncbi.nlm.nih.gov/pubmed/29871524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0963689718775941 |
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