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Design, Characterization, and Evaluation of scFvCD133/rGelonin: A CD133-Targeting Recombinant Immunotoxin for Use in Combination with Photochemical Internalization

The objective of this study was to develop and explore a novel CD133-targeting immunotoxin (IT) for use in combination with the endosomal escape method photochemical internalization (PCI). scFvCD133/rGelonin was recombinantly constructed by fusing a gene (scFvCD133) encoding the scFv that targets bo...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Olsen, Cathrine Elisabeth, Cheung, Lawrence H., Weyergang, Anette, Berg, Kristian, Vallera, Daniel A., Rosenblum, Michael G., Selbo, Pål Kristian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019722/
https://ncbi.nlm.nih.gov/pubmed/31888091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9010068
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