Design, Characterization, and Evaluation of scFvCD133/rGelonin: A CD133-Targeting Recombinant Immunotoxin for Use in Combination with Photochemical Internalization

The objective of this study was to develop and explore a novel CD133-targeting immunotoxin (IT) for use in combination with the endosomal escape method photochemical internalization (PCI). scFvCD133/rGelonin was recombinantly constructed by fusing a gene (scFvCD133) encoding the scFv that targets bo...

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Veröffentlicht in:J Clin Med
Hauptverfasser: Olsen, Cathrine Elisabeth, Cheung, Lawrence H., Weyergang, Anette, Berg, Kristian, Vallera, Daniel A., Rosenblum, Michael G., Selbo, Pål Kristian
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019722/
https://ncbi.nlm.nih.gov/pubmed/31888091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9010068
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