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Identification and characterization of a novel scFv recognizing human and mouse CD133

CD133, also known as Prominin-1, is expressed on stem cells present in many tissues and tumors. In this work, we have identified and characterized a single chain variable fragment (scFv) for efficient and specific recognition of CD133. Phage display was used to develop the scFv from a previously rep...

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Detalhes bibliográficos
Publicado no:Drug Deliv Transl Res
Main Authors: Swaminathan, Suresh Kumar, Niu, Lin, Waldron, Nate, Kalscheuer, Steve, Zellmer, David M., Olin, Michael R., Ohlfest, John R., Vallera, Daniel A., Panyam, Jayanth
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527709/
https://ncbi.nlm.nih.gov/pubmed/25787982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-012-0099-6
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