5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin

BACKGROUND: Development of resistance to 5-fluorouracil (5-FU) is a major problem in treatment of various cancers including pancreatic cancer. In this study, we reveal important resistance mechanisms and photochemical strategies to overcome 5-FU resistance in pancreatic adenocarcinoma. METHODS: 5-FU...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Lund, Kaja, Olsen, Cathrine Elisabeth, Wong, Judith Jing Wen, Olsen, Petter Angell, Solberg, Nina Therese, Høgset, Anders, Krauss, Stefan, Selbo, Pål Kristian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738190/
https://ncbi.nlm.nih.gov/pubmed/29258566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0662-6
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