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Development of a Facile Approach for Generating Chemically Modified CRISPR/Cas9 RNA
The RNA-guided, modified type II prokaryotic CRISPR with CRISPR-associated proteins (CRISPR/Cas9) system represents a simple gene-editing platform with applications in biotechnology and also potentially as a therapeutic modality. The system requires a small guide RNA (sgRNA) and a catalytic Cas9 pro...
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| 發表在: | Mol Ther Nucleic Acids |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Gene & Cell Therapy
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7019045/ https://ncbi.nlm.nih.gov/pubmed/32069700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.01.004 |
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