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Passive immunization with an extended half-life monoclonal antibody protects Rhesus macaques against aerosolized ricin toxin
Inhalation of ricin toxin (RT), a Category B biothreat agent, provokes an acute respiratory distress syndrome marked by pro-inflammatory cytokine and chemokine production, neutrophilic exudate, and pulmonary edema. The severity of RT exposure is attributed to the tropism of the toxin’s B subunit (RT...
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| Veröffentlicht in: | NPJ Vaccines |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7018975/ https://ncbi.nlm.nih.gov/pubmed/32128254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-0162-0 |
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