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Zebrafish as a Model System for the Study of Severe Ca(V)2.1 (α(1A)) Channelopathies
The P/Q-type Ca(V)2.1 channel regulates neurotransmitter release at neuromuscular junctions (NMJ) and many central synapses. CACNA1A encodes the pore-containing α(1A) subunit of Ca(V)2.1 channels. In humans, de novo CACNA1A mutations result in a wide spectrum of neurological, neuromuscular, and move...
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| Publicado no: | Front Mol Neurosci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7018710/ https://ncbi.nlm.nih.gov/pubmed/32116539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00329 |
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