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Zebrafish as a Model System for the Study of Severe Ca(V)2.1 (α(1A)) Channelopathies

The P/Q-type Ca(V)2.1 channel regulates neurotransmitter release at neuromuscular junctions (NMJ) and many central synapses. CACNA1A encodes the pore-containing α(1A) subunit of Ca(V)2.1 channels. In humans, de novo CACNA1A mutations result in a wide spectrum of neurological, neuromuscular, and move...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Mol Neurosci
Prif Awduron: Tyagi, Sidharth, Ribera, Angeles B., Bannister, Roger A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018710/
https://ncbi.nlm.nih.gov/pubmed/32116539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00329
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