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Increased expression of desmin and vimentin reduces bladder smooth muscle contractility via JNK2

Bladder dysfunction is associated with overexpression of the intermediate filament (IF) proteins desmin and vimentin in obstructed bladder smooth muscle (BSM). However, the mechanisms by which these proteins contribute to BSM dysfunction are not known. Previous studies have shown that desmin and vim...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Javed, Elham, Thangavel, Chellappagounder, Frara, Nagat, Singh, Jagmohan, Mohanty, Ipsita, Hypolite, Joseph, Birbe, Ruth, Braverman, Alan S., Den, Robert B, Rattan, Satish, Zderic, Stephen A, Deshpande, Deepak A, Penn, Raymond B., Ruggieri, Michael R., Chacko, Samuel, Boopathi, Ettickan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018560/
https://ncbi.nlm.nih.gov/pubmed/31909533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901301R
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