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SynToxProfiler: An interactive analysis of drug combination synergy, toxicity and efficacy

Drug combinations are becoming a standard treatment of many complex diseases due to their capability to overcome resistance to monotherapy. In the current preclinical drug combination screening, the top combinations for further study are often selected based on synergy alone, without considering the...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Ianevski, Aleksandr, Timonen, Sanna, Kononov, Alexander, Aittokallio, Tero, Giri, Anil K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018095/
https://ncbi.nlm.nih.gov/pubmed/32012154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007604
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