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SynToxProfiler: An interactive analysis of drug combination synergy, toxicity and efficacy

Drug combinations are becoming a standard treatment of many complex diseases due to their capability to overcome resistance to monotherapy. In the current preclinical drug combination screening, the top combinations for further study are often selected based on synergy alone, without considering the...

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Dettagli Bibliografici
Pubblicato in:PLoS Comput Biol
Autori principali: Ianevski, Aleksandr, Timonen, Sanna, Kononov, Alexander, Aittokallio, Tero, Giri, Anil K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018095/
https://ncbi.nlm.nih.gov/pubmed/32012154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007604
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