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SynToxProfiler: An interactive analysis of drug combination synergy, toxicity and efficacy

Drug combinations are becoming a standard treatment of many complex diseases due to their capability to overcome resistance to monotherapy. In the current preclinical drug combination screening, the top combinations for further study are often selected based on synergy alone, without considering the...

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Dades bibliogràfiques
Publicat a:PLoS Comput Biol
Autors principals: Ianevski, Aleksandr, Timonen, Sanna, Kononov, Alexander, Aittokallio, Tero, Giri, Anil K.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018095/
https://ncbi.nlm.nih.gov/pubmed/32012154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007604
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