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Establishment of recombineering genome editing system in Paraburkholderia megapolitana empowers activation of silent biosynthetic gene clusters

The Burkholderiales are an emerging source of bioactive natural products. Their genomes contain a large number of cryptic biosynthetic gene clusters (BGCs), indicating great potential for novel structures. However, the lack of genetic tools for the most of Burkholderiales strains restricts the minin...

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Библиографические подробности
Опубликовано в: :Microb Biotechnol
Главные авторы: Zheng, Wentao, Wang, Xue, Zhou, Haibo, Zhang, Youming, Li, Aiying, Bian, Xiaoying
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017819/
https://ncbi.nlm.nih.gov/pubmed/32053291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1751-7915.13535
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