Peptides containing the MXXCW motif inhibit oncogenic RET kinase activity with a novel mechanism of action

REarranged during Transition (RET) is a tyrosine kinase associated with the development of several malignancies. Identification of RET kinase inhibitors promises valuable therapeutic tools for the intervention of RET-driven tumors. Most currently available tyrosine kinase inhibitors target the ATP b...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Takeda, Kozue, Kawamoto, Yoshiyuki, Nagasaki, Yosuke, Okuno, Yusuke, Goto, Yuko, Iida, Machiko, Yajima, Ichiro, Ohgami, Nobutaka, Kato, Masashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2020
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017734/
https://ncbi.nlm.nih.gov/pubmed/32064171
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge