Peptides containing the MXXCW motif inhibit oncogenic RET kinase activity with a novel mechanism of action

REarranged during Transition (RET) is a tyrosine kinase associated with the development of several malignancies. Identification of RET kinase inhibitors promises valuable therapeutic tools for the intervention of RET-driven tumors. Most currently available tyrosine kinase inhibitors target the ATP b...

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Bibliografski detalji
Izdano u:Am J Cancer Res
Glavni autori: Takeda, Kozue, Kawamoto, Yoshiyuki, Nagasaki, Yosuke, Okuno, Yusuke, Goto, Yuko, Iida, Machiko, Yajima, Ichiro, Ohgami, Nobutaka, Kato, Masashi
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2020
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017734/
https://ncbi.nlm.nih.gov/pubmed/32064171
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