RAS/RAF/MEK/ERK and PI3K/PTEN/AKT Signaling in Malignant Melanoma Progression and Therapy

Cutaneous malignant melanoma is one of the most serious skin cancers and is highly invasive and markedly resistant to conventional therapy. Melanomagenesis is initially triggered by environmental agents including ultraviolet (UV), which induces genetic/epigenetic alterations in the chromosomes of me...

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Bibliografske podrobnosti
Main Authors: Yajima, Ichiro, Kumasaka, Mayuko Y., Thang, Nguyen Dinh, Goto, Yuji, Takeda, Kozue, Yamanoshita, Osamu, Iida, Machiko, Ohgami, Nobutaka, Tamura, Haruka, Kawamoto, Yoshiyuki, Kato, Masashi
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2012
Teme:
Review Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195305/
https://ncbi.nlm.nih.gov/pubmed/22013435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/354191
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