RAS/RAF/MEK/ERK and PI3K/PTEN/AKT Signaling in Malignant Melanoma Progression and Therapy

Cutaneous malignant melanoma is one of the most serious skin cancers and is highly invasive and markedly resistant to conventional therapy. Melanomagenesis is initially triggered by environmental agents including ultraviolet (UV), which induces genetic/epigenetic alterations in the chromosomes of me...

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Main Authors: Yajima, Ichiro, Kumasaka, Mayuko Y., Thang, Nguyen Dinh, Goto, Yuji, Takeda, Kozue, Yamanoshita, Osamu, Iida, Machiko, Ohgami, Nobutaka, Tamura, Haruka, Kawamoto, Yoshiyuki, Kato, Masashi
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2012
主題:
Review Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195305/
https://ncbi.nlm.nih.gov/pubmed/22013435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/354191
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