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TYK2 in Tumor Immunosurveillance
We review the history of the tyrosine kinase 2 (TYK2) as the founding member of the Janus kinase (JAK) family and outline its structure-function relation. Gene-targeted mice and hereditary defects of TYK2 in men have established the biological and pathological functions of TYK2 in innate and adaptiv...
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| Pubblicato in: | Cancers (Basel) |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7017180/ https://ncbi.nlm.nih.gov/pubmed/31936322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010150 |
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