Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages

Silicosis is an occupational lung disease characterized by persistent inflammation and irreversible fibrosis. Crystalline silica (CS) particles are mainly phagocytized by alveolar macrophages (AMs), which trigger apoptosis, inflammation, and pulmonary fibrosis. Previously, we found that autophagy-ly...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cells
Päätekijät: He, Xiu, Chen, Shi, Li, Chao, Ban, Jiaqi, Wei, Yungeng, He, Yangyang, Liu, Fangwei, Chen, Ying, Chen, Jie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016807/
https://ncbi.nlm.nih.gov/pubmed/31947943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010122
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia