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Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages

Silicosis is an occupational lung disease characterized by persistent inflammation and irreversible fibrosis. Crystalline silica (CS) particles are mainly phagocytized by alveolar macrophages (AMs), which trigger apoptosis, inflammation, and pulmonary fibrosis. Previously, we found that autophagy-ly...

詳細記述

保存先:
書誌詳細
出版年:Cells
主要な著者: He, Xiu, Chen, Shi, Li, Chao, Ban, Jiaqi, Wei, Yungeng, He, Yangyang, Liu, Fangwei, Chen, Ying, Chen, Jie
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016807/
https://ncbi.nlm.nih.gov/pubmed/31947943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010122
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