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TFEB and trehalose drive the macrophage autophagy-lysosome system to protect against atherosclerosis

In the atherosclerotic plaque, macrophages are the key catabolic workhorse responsible for clearing lipid and dead cell debris. To survive the highly proinflammatory and lipotoxic plaque environment, macrophages must adopt strategies for maintaining tight homeostasis and self-renewal. Macroautophagy...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Evans, Trent D., Jeong, Se-Jin, Zhang, Xiangyu, Sergin, Ismail, Razani, Babak
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959328/
https://ncbi.nlm.nih.gov/pubmed/29394113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1434373
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