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TFEB and trehalose drive the macrophage autophagy-lysosome system to protect against atherosclerosis
In the atherosclerotic plaque, macrophages are the key catabolic workhorse responsible for clearing lipid and dead cell debris. To survive the highly proinflammatory and lipotoxic plaque environment, macrophages must adopt strategies for maintaining tight homeostasis and self-renewal. Macroautophagy...
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| Publicado no: | Autophagy |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5959328/ https://ncbi.nlm.nih.gov/pubmed/29394113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1434373 |
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