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TFEB and trehalose drive the macrophage autophagy-lysosome system to protect against atherosclerosis

In the atherosclerotic plaque, macrophages are the key catabolic workhorse responsible for clearing lipid and dead cell debris. To survive the highly proinflammatory and lipotoxic plaque environment, macrophages must adopt strategies for maintaining tight homeostasis and self-renewal. Macroautophagy...

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Bibliografiska uppgifter
I publikationen:Autophagy
Huvudupphovsmän: Evans, Trent D., Jeong, Se-Jin, Zhang, Xiangyu, Sergin, Ismail, Razani, Babak
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959328/
https://ncbi.nlm.nih.gov/pubmed/29394113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1434373
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