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TFEB and trehalose drive the macrophage autophagy-lysosome system to protect against atherosclerosis

In the atherosclerotic plaque, macrophages are the key catabolic workhorse responsible for clearing lipid and dead cell debris. To survive the highly proinflammatory and lipotoxic plaque environment, macrophages must adopt strategies for maintaining tight homeostasis and self-renewal. Macroautophagy...

詳細記述

保存先:
書誌詳細
出版年:Autophagy
主要な著者: Evans, Trent D., Jeong, Se-Jin, Zhang, Xiangyu, Sergin, Ismail, Razani, Babak
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959328/
https://ncbi.nlm.nih.gov/pubmed/29394113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1434373
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