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DEGRADATION AND BEYOND: THE MACROPAHGE LYSOSOME AS A NEXUS FOR NUTRIENT SENSING AND PROCESSING IN ATHEROSCLEROSIS

PURPOSE OF REVIEW: The ability of macrophage lysosomes to degrade both exogenous and internally derived cargo is paramount to handling the overabundance of lipid and cytotoxic material present in the atherosclerotic plaque. We will discuss recent insights in both classical and novel functions of the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Curr Opin Lipidol
Prif Awduron: Sergin, Ismail, Evans, Trent, Razani, Babak
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027838/
https://ncbi.nlm.nih.gov/pubmed/26241101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOL.0000000000000213
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