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DEGRADATION AND BEYOND: THE MACROPAHGE LYSOSOME AS A NEXUS FOR NUTRIENT SENSING AND PROCESSING IN ATHEROSCLEROSIS

PURPOSE OF REVIEW: The ability of macrophage lysosomes to degrade both exogenous and internally derived cargo is paramount to handling the overabundance of lipid and cytotoxic material present in the atherosclerotic plaque. We will discuss recent insights in both classical and novel functions of the...

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Bibliografiske detaljer
Udgivet i:Curr Opin Lipidol
Main Authors: Sergin, Ismail, Evans, Trent, Razani, Babak
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027838/
https://ncbi.nlm.nih.gov/pubmed/26241101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOL.0000000000000213
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