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DEGRADATION AND BEYOND: THE MACROPAHGE LYSOSOME AS A NEXUS FOR NUTRIENT SENSING AND PROCESSING IN ATHEROSCLEROSIS

PURPOSE OF REVIEW: The ability of macrophage lysosomes to degrade both exogenous and internally derived cargo is paramount to handling the overabundance of lipid and cytotoxic material present in the atherosclerotic plaque. We will discuss recent insights in both classical and novel functions of the...

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Bibliografski detalji
Izdano u:Curr Opin Lipidol
Glavni autori: Sergin, Ismail, Evans, Trent, Razani, Babak
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027838/
https://ncbi.nlm.nih.gov/pubmed/26241101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOL.0000000000000213
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