Dysregulated metabolic pathways in age-related macular degeneration

Age-related macular degeneration is a major cause of vision impairment in the Western world among people of 55 years and older. Recently we have shown that autophagy is dysfunctional in the retinal pigment epithelium (RPE) of the AMD donor eyes (AMD RPE). We also showed increased reactive oxygen (RO...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Meng, Jiang, Nisi, Chu, Yi, Postnikova, Olga, Varghese, Rency, Horvath, Anelia, Cheema, Amrita K., Golestaneh, Nady
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016007/
https://ncbi.nlm.nih.gov/pubmed/32051464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59244-4
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