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Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration

Age-related macular degeneration (AMD) is a devastating neurodegenerative disease and a major cause of blindness in the developed world. Owing to its complexity and the lack of an adequate human model that recapitulates key aspects of the disease, the molecular mechanisms of AMD pathogenesis remain...

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Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Golestaneh, Nady, Chu, Yi, Xiao, Yang-Yu, Stoleru, Gianna L, Theos, Alexander C
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386365/
https://ncbi.nlm.nih.gov/pubmed/28055007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.453
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