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Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration

Age-related macular degeneration (AMD) is a devastating neurodegenerative disease and a major cause of blindness in the developed world. Owing to its complexity and the lack of an adequate human model that recapitulates key aspects of the disease, the molecular mechanisms of AMD pathogenesis remain...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Golestaneh, Nady, Chu, Yi, Xiao, Yang-Yu, Stoleru, Gianna L, Theos, Alexander C
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386365/
https://ncbi.nlm.nih.gov/pubmed/28055007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.453
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