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Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration

Age-related macular degeneration (AMD) is a devastating neurodegenerative disease and a major cause of blindness in the developed world. Owing to its complexity and the lack of an adequate human model that recapitulates key aspects of the disease, the molecular mechanisms of AMD pathogenesis remain...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Golestaneh, Nady, Chu, Yi, Xiao, Yang-Yu, Stoleru, Gianna L, Theos, Alexander C
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386365/
https://ncbi.nlm.nih.gov/pubmed/28055007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.453
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