Dysregulated metabolic pathways in age-related macular degeneration

Age-related macular degeneration is a major cause of vision impairment in the Western world among people of 55 years and older. Recently we have shown that autophagy is dysfunctional in the retinal pigment epithelium (RPE) of the AMD donor eyes (AMD RPE). We also showed increased reactive oxygen (RO...

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Published in:Sci Rep
Main Authors: Zhang, Meng, Jiang, Nisi, Chu, Yi, Postnikova, Olga, Varghese, Rency, Horvath, Anelia, Cheema, Amrita K., Golestaneh, Nady
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016007/
https://ncbi.nlm.nih.gov/pubmed/32051464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59244-4
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