Targeting Src family kinase member Fyn by Saracatinib attenuated liver fibrosis in vitro and in vivo

Recent studies suggest that Src family kinase (SFK) plays important roles in systemic sclerosis and pulmonary fibrosis. However, how SFKs contributed to the pathogenesis of liver fibrosis remains largely unknown. Here, we investigated the role of Fyn, a member of SFK, in hepatic stellate cell (HSC)...

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Publicado en:Cell Death Dis
Autores principales: Du, Guifang, Wang, Jing, Zhang, Ting, Ding, Qiang, Jia, Xiaodong, Zhao, Xueke, Dong, Jinke, Yang, Xinrui, Lu, Shanshan, Zhang, Cuihong, Liu, Ze, Zeng, Zhen, Safadi, Rifaat, Qi, Ruizhao, Zhao, Xin, Hong, Zhixian, Lu, Yinying
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016006/
https://ncbi.nlm.nih.gov/pubmed/32051399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2229-2
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