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Targeting Src family kinase member Fyn by Saracatinib attenuated liver fibrosis in vitro and in vivo

Recent studies suggest that Src family kinase (SFK) plays important roles in systemic sclerosis and pulmonary fibrosis. However, how SFKs contributed to the pathogenesis of liver fibrosis remains largely unknown. Here, we investigated the role of Fyn, a member of SFK, in hepatic stellate cell (HSC)...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Du, Guifang, Wang, Jing, Zhang, Ting, Ding, Qiang, Jia, Xiaodong, Zhao, Xueke, Dong, Jinke, Yang, Xinrui, Lu, Shanshan, Zhang, Cuihong, Liu, Ze, Zeng, Zhen, Safadi, Rifaat, Qi, Ruizhao, Zhao, Xin, Hong, Zhixian, Lu, Yinying
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016006/
https://ncbi.nlm.nih.gov/pubmed/32051399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2229-2
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