Vitamin D repletion ameliorates adipose tissue browning and muscle wasting in infantile nephropathic cystinosis‐associated cachexia

BACKGROUND: Ctns(−/−) mice, a mouse model of infantile nephropathic cystinosis, exhibit hypermetabolism with adipose tissue browning and profound muscle wasting. Ctns(−/−) mice are 25(OH)D(3) and 1,25(OH)(2)D(3) insufficient. We investigated whether vitamin D repletion could ameliorate adipose tissu...

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Veröffentlicht in:J Cachexia Sarcopenia Muscle
Hauptverfasser: Cheung, Wai W., Hao, Sheng, Wang, Zhen, Ding, Wei, Zheng, Ronghao, Gonzalez, Alex, Zhan, Jian‐Ying, Zhou, Ping, Li, Shiping, Esparza, Mary C., Hoffman, Hal M., Lieber, Richard L., Mak, Robert H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015252/
https://ncbi.nlm.nih.gov/pubmed/31721480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12497
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