Vitamin D repletion ameliorates adipose tissue browning and muscle wasting in infantile nephropathic cystinosis‐associated cachexia

BACKGROUND: Ctns(−/−) mice, a mouse model of infantile nephropathic cystinosis, exhibit hypermetabolism with adipose tissue browning and profound muscle wasting. Ctns(−/−) mice are 25(OH)D(3) and 1,25(OH)(2)D(3) insufficient. We investigated whether vitamin D repletion could ameliorate adipose tissu...

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Bibliografske podrobnosti
izdano v:J Cachexia Sarcopenia Muscle
Main Authors: Cheung, Wai W., Hao, Sheng, Wang, Zhen, Ding, Wei, Zheng, Ronghao, Gonzalez, Alex, Zhan, Jian‐Ying, Zhou, Ping, Li, Shiping, Esparza, Mary C., Hoffman, Hal M., Lieber, Richard L., Mak, Robert H.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015252/
https://ncbi.nlm.nih.gov/pubmed/31721480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12497
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