Vitamin D repletion ameliorates adipose tissue browning and muscle wasting in infantile nephropathic cystinosis‐associated cachexia

BACKGROUND: Ctns(−/−) mice, a mouse model of infantile nephropathic cystinosis, exhibit hypermetabolism with adipose tissue browning and profound muscle wasting. Ctns(−/−) mice are 25(OH)D(3) and 1,25(OH)(2)D(3) insufficient. We investigated whether vitamin D repletion could ameliorate adipose tissu...

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Detalhes bibliográficos
Publicado no:J Cachexia Sarcopenia Muscle
Main Authors: Cheung, Wai W., Hao, Sheng, Wang, Zhen, Ding, Wei, Zheng, Ronghao, Gonzalez, Alex, Zhan, Jian‐Ying, Zhou, Ping, Li, Shiping, Esparza, Mary C., Hoffman, Hal M., Lieber, Richard L., Mak, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015252/
https://ncbi.nlm.nih.gov/pubmed/31721480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12497
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