Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway

BACKGROUND: Skeletal muscle is mainly responsible for insulin‐stimulated glucose disposal. Dysfunction in skeletal muscle metabolism especially during obesity contributes to the insulin resistance. Astaxanthin (AX), a natural antioxidant, has been shown to ameliorate hepatic insulin resistance in ob...

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Pubblicato in:J Cachexia Sarcopenia Muscle
Autori principali: Nishida, Yasuhiro, Nawaz, Allah, Kado, Tomonobu, Takikawa, Akiko, Igarashi, Yoshiko, Onogi, Yasuhiro, Wada, Tsutomu, Sasaoka, Toshiyasu, Yamamoto, Seiji, Sasahara, Masakiyo, Imura, Johji, Tokuyama, Kumpei, Usui, Isao, Nakagawa, Takashi, Fujisaka, Shiho, Kunimasa, Yagi, Tobe, Kazuyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015247/
https://ncbi.nlm.nih.gov/pubmed/32003547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12530
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