mTORC1 signalling is not essential for the maintenance of muscle mass and function in adult sedentary mice

BACKGROUND: The balance between protein synthesis and degradation (proteostasis) is a determining factor for muscle size and function. Signalling via the mammalian target of rapamycin complex 1 (mTORC1) regulates proteostasis in skeletal muscle by affecting protein synthesis and autophagosomal prote...

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書目詳細資料
發表在:J Cachexia Sarcopenia Muscle
Main Authors: Ham, Alexander S., Chojnowska, Kathrin, Tintignac, Lionel A., Lin, Shuo, Schmidt, Alexander, Ham, Daniel J., Sinnreich, Michael, Rüegg, Markus A.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
主題:
Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015237/
https://ncbi.nlm.nih.gov/pubmed/31697050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12505
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